Cassava, konzo, and neurotoxicity
نویسندگان
چکیده
منابع مشابه
Konzo and continuing cyanide intoxication from cassava in Mozambique.
In Mozambique, epidemics of the cassava-associated paralytic disease, konzo, have been reported in association with drought or war: over 1100 cases in 1981, over 600 cases in 1992-1993, and over 100 cases in 2005. Smaller epidemics and sporadic cases have also been reported. Large epidemics have occurred at times of agricultural crisis, during the cassava harvest, when the population has been d...
متن کاملPersistent konzo and cyanogen toxicity from cassava in northern Mozambique.
We aimed to detect new cases of konzo and monitor cyanogen exposure from cassava flour in communities previously affected by konzo epidemics in Nampula Province, northern Mozambique. Other objectives were to detect subclinical upper motor neuron damage in schoolchildren and test a new kit to measure urinary thiocyanate concentration. In 1999 and 2000, we carried out active and passive case dete...
متن کاملKonzo, TAN and cyanogens from cassava flour and gari. ..1 Cassava utilization in Busia
Konzo is an irreversible paralysis of the legs that occurs mainly in children and women of child bearing age in Mozambique, Tanzania, Democratic Republic of Congo (DRC), Cameroon, Central African Republic (CAR) and probably other countries. It is an upper motor neuron disease of sudden onset due to large intakes of cyanide from cassava over a fairly short period. Epidemics may occur as a result...
متن کاملKonzo, TAN and cyanogens from cassava flour and gari. ..1 Cassava utilization in Busia
Konzo is an irreversible paralysis of the legs that occurs mainly in children and women of child bearing age in Mozambique, Tanzania, Democratic Republic of Congo (DRC), Cameroon, Central African Republic (CAR) and probably other countries. It is an upper motor neuron disease of sudden onset due to large intakes of cyanide from cassava over a fairly short period. Epidemics may occur as a result...
متن کاملUptake of wetting method in Africa to reduce cyanide poisoning and konzo from cassava.
Cassava contains cyanogenic glucosides which are hydrolysed by an enzyme linamarase to produce cyanohydrins which breakdown to toxic cyanide. Cyanide ingestion from bitter cassava can cause cyanide poisoning sometimes leading to death and also konzo, an irreversible paralysis of the legs which occurs mainly in children and young women. In 2005 we developed a simple wetting method that reduces t...
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ژورنال
عنوان ژورنال: The Lancet Global Health
سال: 2017
ISSN: 2214-109X
DOI: 10.1016/s2214-109x(17)30306-6